Reproductive Tox

Pristima provides you with a single solution to handle all typical and atypical reproductive toxicology study designs including fertility and fetal development, post-natal development and multi-generation studies.   Measurements, notes and observations may be conducted on adult animals, offspring or even non-animal subjects such as rooms and cages.

Key advantages include:
  • Study management tools
    • Automatic randomization and manual assignment of animals to groups
    • Automatic Assignment of animal start dates – unlimited number of staggers based on mating or delivery dates
    • Assignment of animals to cages – one or multiple animals per cage
    • Assignment of animal RFID implant chips
    • Assignment of blinding number to each animal – beneficial for blind data entry on Teratology studies
  • Protocol-driven activities:
    • 1 to 4 generations of animals per study
    • Online capture of body weights
    • Online capture of food and water consumption
    • All types of clinical observations including dose-response (time sensitive) observations
    • Online dose administration including barcoded confirmation of the dose container
    • Online sample collection (blood, urine, sperm, milk, etc…)
    • Site-specific custom measurements
    • Parturition data including births, deaths and delivery time
    • Pup and litter assessments and measurements
    • Online capture of final maternal body weights – which are checked against the most recent in-vivo weights
    • Online capture of organ weights – which are checked against the final body weight
    • Macroscopic observations – which are checked against clinical signs
    • Tissue accountability and tracking
    • C-section implant and CL counts
    • Uterine examination and fetal measurements
    • Fetal fresh and fixed pathology
  • Daily Completion checks – activity monitor provides study managers with views of complete/incomplete activities
  • Online data reviews – allows the study director to electronically approve and sign the data
  • Built-in reporting, summarization and visualization of data by group, litter or individual animal
  • Built-in statistical library with user-definable decision trees integrated directly into report compilation