Pristima provides you with a single solution to handle all typical and atypical reproductive toxicology study designs including fertility and fetal development, post-natal development and multi-generation studies. Measurements, notes and observations may be conducted on adult animals, offspring or even non-animal subjects such as rooms and cages.
Key advantages include:
- Study management tools
- Automatic randomization and manual assignment of animals to groups
- Automatic Assignment of animal start dates – unlimited number of staggers based on mating or delivery dates
- Assignment of animals to cages – one or multiple animals per cage
- Assignment of animal RFID implant chips
- Assignment of blinding number to each animal – beneficial for blind data entry on Teratology studies
- Protocol-driven activities:
- 1 to 4 generations of animals per study
- Online capture of body weights
- Online capture of food and water consumption
- All types of clinical observations including dose-response (time sensitive) observations
- Online dose administration including barcoded confirmation of the dose container
- Online sample collection (blood, urine, sperm, milk, etc…)
- Site-specific custom measurements
- Parturition data including births, deaths and delivery time
- Pup and litter assessments and measurements
- Online capture of final maternal body weights – which are checked against the most recent in-vivo weights
- Online capture of organ weights – which are checked against the final body weight
- Macroscopic observations – which are checked against clinical signs
- Tissue accountability and tracking
- C-section implant and CL counts
- Uterine examination and fetal measurements
- Fetal fresh and fixed pathology
- Daily Completion checks – activity monitor provides study managers with views of complete/incomplete activities
- Online data reviews – allows the study director to electronically approve and sign the data
- Built-in reporting, summarization and visualization of data by group, litter or individual animal
- Built-in statistical library with user-definable decision trees integrated directly into report compilation
